Reply to lovenox and mthfr gene

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[quote=Anonymous][quote=Anonymous]Regardless of if you take lovenox or not, be sure you take Metanx- a prescription strength folic acid. With the MTHFR gene, your body has a hard time converting folic acid into its usable form, L-methylfolate. Metanx is folic acid already in the L-methylfolate form so your body can absorb it. Taking extra regular folic acid does not help. Many doctors will prescribe a similar prescription strength folic acid, Folgard, but anyone who really specializes in this says that Metanx is definitely the way to go. Without it, you run the risk of increased down syndrome and other neural tube defects (there have also been some recent studies showing a link between MTHFR and autism if not properly treated during pregnancy). Insurance usually doesn't cover it and its like $60 a month. In case your doctor hasn't prescribed it, definitely ask them to!

My insurance covers my lovenox and I also take a baby aspirin among other things. I have MTHFR plus one other blood clotting disorders plus immune issues. (Often immune issues and blood clotting disorders come hand in hand). Lovenox helps both because it is an anti-inflammatory and when you have immune issues, your body will send small blood clots to kill the fetus- something that is made easier when you have a blood clotting disorder.

After your two losses, I wouldn't take the risk and would go ahead and use the lovenox. It can help so much with implantation issues which could likely be the cause of your early miscarriages. You might only need it for the first trimester and if you do need it throughout the pregnancy, some doctors switch you to heparin in the last month- which leaves your body quicker so you can still do an epidural or will schedule you for induction and you stop the lovenox 24 hours before delivery.

A high risk OB who specializes in blood clotting disorders in the area is named Dr. Hamersely. She is based in Rockville with Maternal Fetal Medicine Associates of Maryland. She accepts most insurance so you may want to get a second opinion from her. She is one of the top specialists in blood clotting disorders in pregnancy in the country and writes most of the standard protocols. [/quote]

I second the rec for Dr. Hamersly.  She is an amazing doc and she specializes in clotting disorders.  I've had two sucessful pregnancies under her care and I have MTHFR and PAI-1 mutation along with lupus.  She will see you right away if you tell the receptionist that you are newly pregnany after two losses and have a confirmed clotting disorder.  I would let her make the determination on your treatment plan.[/quote]

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