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Infertility Support and Discussion
Reply to "Anyone experienced total fertilization failure with ICSI?"
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[quote=Anonymous]Hello I am 37 and DH is 39 My husband was diagnosed with azoospermia and had to go through TESE to retrieve sperm. We tried 2 IVF cycles; both with ICSI and there was NO fertilization. IVF 1: 7 mature eggs IVF 2: 5 mature eggs They don't know why there was no fertilization. Seems that the eggs were not activated. Morphologically the eggs looked good both times; and the sperm used was thought to be optimal for fertilization. But nothing happened both times. After the first cycle we thought it could have been a lab error that none of the eggs fertilized with ICSI. But it happened a 2nd time :( The clinic is recommending using fresh sperm and fresh eggs (DH has to do another TESE and coordinate his surgery the same day as my egg retrieval). They do not know why there wasn't fertilization both times. We were told that sometimes the sperm and egg "looks good" but no fertilization is achieved. Another option they are suggesting is to test some eggs with a donor sperm to see if any will fertilize; this way they can rule out if the issue is with the eggs. [/quote]
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