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[quote=Anonymous][quote=Anonymous]HI everyone,

I would really appreciate hearing if anyone has experienced total fertilization failure with ICSI. A bit of background: I am 42 years old and have had 6 cycles of IVF over the past two years - 2 in Canada, 1 at Shady Grove and 3 at CCRM NOVA. For the last 3 cycles we have been blastocyst banking without testing. I am a high responder with high AMH and typically retrieve between 15 - 18 eggs. For this past cycle (which was to be our last baking cycle), they retrieved 25 eggs, with 19 mature. However none fertilized with ICSI. We are in absolute shock as we have always had average or above average fertilization rates (average across prior cycles of 76%). We are doing back to back cycles, so no real time has passed since our last cycle in June, where 75% of eggs fertilized. CCRM has indicated they have no idea why this happened as eggs and sperm were both excellent quality. Any insight is much appreciated![/quote]

Hi there- in two cycles we failed to get blasts there. Fert rate was 50-60% but they all failed before day 5. Switched clinics and ended up with 3 blasts. After failure #1 donor was brought up which rubbed us the wrong way after only one failed cycle. [/quote]

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