Reply to My Day 3 infertility testing has not changed much in 5 years

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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]Also your estradiol was always too high, so your FSH was probably over 10 at 38 which is bad.

I was incredibly lucky to have gotten pregnant several times starting at 38. My AMH was low throughout (all my IVFs failed) but my FSH was always under 10 and my estradiol was in low 20s even at 44.[/quote]

I thought low estradiol is bad.  Can you explain why high estradiol levels are bad?  I'm unclear about this.

Also my FSH between age 38-40 ranged from 5-10 on the three times it was measured during those ranges but still no luck in getting pregnant.[/quote]

only the highest FSH is relevant. high FSH indicates that eggs are not signaling well which they think is related to their quality. if you hit 10 at 38 that would indicate low quality for your age.

as for estradiol, it masks your FSH making it seem lower (i.e. better) than it is. so if you FSH was 8 while your estradiol is 40s that means your "real" FSH is more like 10 or 12.

this is independent on whether high estradiol is good or bad. the point is that it makes FSH (which is more important) look better than it is and needs to be taken into account.

as for estradiol itself... low is not good when combined with other hormones which indicate menopause. however, i think the doctors don't quite understand the levels and how they relate to infertility. my own hunch is that estradiol needs to be low (e.g. low 20s) but also climb very sharply before ovulation.[/quote]

OP here.  Okay, so if an FSH of 10 at age 38 implies low quality eggs for my age, how did I get pregnant on the first try at 36?  I have no idea what my hormones were at 36 when I got pregnant because I didn't have an infertility problem then.  Is it possible to have normal fertility for my age at 36 and then two years later be completely infertile?  This is what I don't really understand, how the decline could happen so sharply.  My AMH at 38 was .60 which is already low.  At 36 could it really have been that much higher?[/quote]

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