Reply to Kids and Miralax - how to make it better to take?

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[quote=Anonymous][quote=Anonymous]Daily doses of Miralax are possibly dangerous to kids.

Miralax is only indicated for adults, and for usage no longer than one week. CHOP is doing a study on neurological issues that they’re finding in kids who have taken lots of it. You should look into it.

Put him on the natural calm powder at night (not the kind with calcium). As PP said, Mg really moves the bowels.

If he was a heavy milk drinker, that was likely what was constipating him. I’d push water on him, and try the magnesium.

[/quote]

This gets posted about here on DCUM a lot. It is often misrepresented, whether deliberately or not.

To be clear, the CHOP study was in response to parental concerns and social media discussions filled with guesswork and misinformation. It's not being done because a researcher thinks that Miralax is probably a problem -- it's being done to settle the question, same as studies were done to settle the faux MMR/autism connection question.

As CHOP states in the original research brief, "At this time, however, we are not aware of any scientific study indicating that PEG 3350 is dangerous or causes neurobehavioral symptoms." https://heuckeroth.research.chop.edu/peg-3350-study

CHOP still recommends Miralax for pediatric colonoscopy preps: https://www.chop.edu/centers-programs/kohl-s-gi-nutrition-and-diagnostic-center/colonoscopy-preparation

NASPGHAN (The North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition) has a FAQ about Miralax here (PDF): https://cmcpediatrics.com/wp-content/uploads/2015/01/PEG-3350-FAQ.pdf

[quote]8.  [b]Why is the FDA sponsoring a new study on the safety of PEG 3350 and what new information do they hope to find out?[/b]  
The FDA is interested in investigating the safety of PEG 3350 use in children and for prolonged periods. Although PEG 3350 is a very large molecule which is not absorbed by the gut due to its size, there are concerns that smaller compounds, such as ethylene glycol or diethylene glycol, could be found as impurities in the manufacturing process of PEG 3350 or formed when PEG 3350 is broken down within the body. The FDA is investigating if these smaller compounds are absorbed by the gut and accumulated in the bodies of children taking PEG 3350. Some families have reported concerns to the FDA that some neurologic or behavioral symptoms in children may be related to taking PEG 3350. It is unclear whether these side-effects are due to PEG 3350. This study is the first step towards trying to determine if there is truly a link.

[b]10.  What should I do if my child is currently taking PEG 3350? [/b]
 
Generally speaking, if your child has been prescribed PEG 3350 as part of his/her treatment plan, and you feel this medicine provides benefit, you should feel safe continuing PEG 3350. At this time, PEG 3350 appears to be safe based on current medical literature. We recommend discussing any concerns you have about the safety of PEG 3350 with your child’s health care provider. If you would prefer for your child to stop taking PEG 3350, discuss other treatments options with your child’s health care team before stopping PEG 3350 therapy. Although abruptly stopping PEG 3350 is not considered dangerous, it could lead to a relapse/worsening of constipation.    [/quote][/quote]

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