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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]Minimal stimulation starting with a few days of Clomid and leading into injections not to exceed 150 or 175 IUs of Follistim a day + no more than one vial of Menopur. This did wonders for my cycles. I produced more eggs of higher quality. Good luck, OP. I also had to go out of state. [/quote]

I just emailed with my doc and she recommends doing estrogen priming along with a mini stim of max 225 IUs.  What do you base the "not to exceed 150-175 IUs of Follistim" on?  And what is the difference between Clomid priming, if you will, and estrogen priming?
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To clarify, you can do EPP and clomid in the same cycle.  Clomid is used as part of a low dose/mini stim cycle and as part of the stim meds.  EPP or BCP are the ways to prep the ovaries so that you start the cycle with all the eggs at the same stage, so as many as possible are ready at the same time.  BCP can be overly suppressive, so the EPP method is often used for DOR or older people.  Both BCP and EPP involve estrogen taken prior to the start of a cycle, just in different ways/amounts.

I did this type of cycle at Dominion, but the idea came from a Cornell consult and a lot of research on my part b/c I didn't have DOR, but am older.  This cycle was much better for my egg quality (I did also take ubiquinol and fish oil and later a lower dose of DHEA, of those I can only say that ubiquinol was clearly helpful).  When I talked to Cornell, they basically said it was a good option if you knew you'd only get a few eggs anyway, and they focused on doing a day 3 transfer and other lab differences they thought were important.  So initially I didn't go with them b/c I was thinking that its all a #s game (which is not entirely true), and I did go on to SG and do cycles with plenty of eggs, but no blasts.  We had MF issues, too, so I chased down whether that was the issue as some docs say it is when you don't get blasts, but it most certainly wasn't (DH had normal DNA frag test and DE cycle results were perfect with very high fertilization rate).  As I looked into it further, I found info that suggested that high stims can be bad for quality, esp menopur, so I tried the mini, and while I had much better results (higher fert rate and more blasts), it wasn't successful (chemical) and I had already been going for a couple years and had gotten even older, so I decided to stop there.  I do wish I'd gotten there much sooner and would have been able to try that protocol several times and a couple years younger, but I did what I thought best based on the info I had at the time, so no regrets - just frustration at the lack of reliable info in the process.  I did DE and it worked, but feel like I should share info since I got ideas for things to look into from this and other boards.

Unfortunately, the research in this area isn't great and lots of docs have their go-to thing that's often based on their own limited experiences rather than good data.  Anyway - I know it's tough to sort through the info, but I hope you're successful!

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