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Reply to "Your best tips and recommended protocols for DOR?"
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[quote=Anonymous][quote=Anonymous][quote=Anonymous]Minimal stimulation starting with a few days of Clomid and leading into injections not to exceed 150 or 175 IUs of Follistim a day + no more than one vial of Menopur. This did wonders for my cycles. I produced more eggs of higher quality. Good luck, OP. I also had to go out of state. [/quote] I just emailed with my doc and she recommends doing estrogen priming along with a mini stim of max 225 IUs. What do you base the "not to exceed 150-175 IUs of Follistim" on? And what is the difference between Clomid priming, if you will, and estrogen priming? Also, why did you have to go out state? No one in the area would do this protocol? Thanks.[/quote] Hi PP. I suggested that particular number because that was basically my protocol at Cornell. I did I think 4 retrievals with them. They are widely lauded on this board to be a great clinic for those with DOR. Of course, our bodies are all different so what worked well for me might not work for you, and I think starting out with your doctor's suggested protocol is fine, and then if that doesn't work, maybe go down from there. I am not sure I can explain the scientific differences between estrogen priming and Clomid... only that EPP by itself never worked well for me. With Clomid added, I saw a marked increase in my follicle count. What I forgot to mention in my first post is that Cornell actually DID start me on estrogen patches (as opposed to BCP). If you are interested, I have everything in a Google calendar. So yes, I began with a patch, then started stimming with Clomid, then added in the injections. I always start out with a decent AFC (10-20) and then, when I was on high stims, by the time I got to retrieval, we'd get 4-6 eggs. I would always go for monitoring at Cornell after taking the first few doses of Clomid and marvel at the screen. The doctors doing the monitoring would always attribute things to the Clomid. Upon my first retrieval there, they got 25 eggs. I was shocked, since I came from a Dr at SG who said I had DOR. That said, it does have a tendency to thin your lining... though it rarely inhibited implantation for me. I went out of state because my doctor at SG was not very receptive to me changing up my protocol and I was just over it. By the time I was done at Shady Grove I was just so down and fed up that I wanted to find "the best" clinic (and I did meet with one of the CFA doctors before I chose to go out of state but she was very pessimistic about my case). I was in between CCRM and Cornell and chose Cornell. [/quote]
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