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[quote=Anonymous]It's not a scam, but also not a magic bullet.  After lots of research and experience, I currently think that PGS is great for those who will have many blasts.  Even in young, healthy women, about 50% of blasts will be abnormal.  With PGS, you can figure out which embryos have the best chance and transfer those, potentially saving time, $ and lowering miscarriage risk.

For older women who produce few blasts, it's not that helpful.  Most to all blasts for older women will be abnormal.  There is evidence to suggest that PGS may show an embryo as abnormal that could have resulted in a healthy baby, although it's rare. Also, the biopsy procedure does pose some risk to the blasts.  If you're older with few blasts, you probably don't want to take the chance with PGS.  Plus, I think the charge is the same for the first 8 or so blasts, so if you only have a few at a time, it's also not great economically.  (You can bank and test, but then you get into thawing and refreezing, which is even more risk to the blasts).  While there is a chance that you may miscarry, in many cases, abnormal embryos will result in a BFN or chemical, so I don't think that the possibility of miscarriage outweighs the negatives of PGS in cases of older women who have few blasts.  Docs may like PGS even for older women since if you do get a normal blast, the odds that it will result in a pregnancy are much higher.

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