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Infertility Support and Discussion
Reply to "Experience with Male Factor"
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[quote=Anonymous]I realize that you're getting a lot of information here, and that some of it conflicts. I am simply passing along with what our male factor RE told us. He was very well respected, but there is so much they/we don't know that I just add this for your consideration. Oddly enough, we were advised AGAINST ICSI. Our male RE believed that ICSI was only needed if you had a protein barrier problem (the sperm did not have the enzyme/protein to break down the egg wall). This is a very easy test to have done. The male RE's view was that, barring that problem, you reduced the likelihood of "bad sperm" getting into an egg by letting them fight it out, even in the tiny arena of the petri dish. This is for two reasons. One, in his view, the more normal sperm will swim better and penetrate faster. Two, the egg actually communicates with the sperm and can be said to "choose" the sperm. ICSI bypasses that natural process, and, in his view, may have an impact on the resulting embryo quality. So what did we do with that information? Hedged our bets of course! We did half ICSI/half regular. We got 6 to blast. 3 failed. The Fourth is DS. We have two left in the freezer. DS was not an ICSI baby. Two of the three failed embryos were ICSI. This is NOT a statistical sample obviously! Just letting you know :) For us, we wouldn't do ICSI again, given that we didn't have fertilization problems in the test or with my eggs. So let the best man win :) [/quote]
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