Reply to Fetal Fraction at 21 weeks

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[quote=Anonymous][quote=Anonymous][quote=Anonymous]I'm a high risk pregnancy due to recurrent miscarriage with trisomy, PCOS, and hypothyroidism. Instead of the traditional second trimester screening, I opted for the MaterNiT21 test. Thankfully, the test came back negative for Trisomy 21/13/18. The odd thing is, my fetal fraction was only 7%. That seems low for 21 weeks gestation. I understand it is high enough to be accurate for the trisomy screenings, but the actual fraction seems like it should be higher.

I'm not overweight. My check up the other day revealed a heartrate of 153, normal blood pressure, normal thyroid levels, normal glucose levels, a normal fundal height, I've gained 12lbs since pre-pregnancy, and the baby is kicking away. I take 112mg of Synthroid and 1000mg of Metformin each day.

Perhaps I'm just worried due to my previous pregnancy losses. Does my fetal fraction mean anything? [/quote]

If it’s high enough to be accurate according to the lab, don’t worry.  I don’t even have any idea what the average fraction is.  Try to relax.  Congrats![/quote]

Thank you for the response. Honestly, I can't find too much info on average fetal fractions. After receiving my MaterniT21 report, I saw fetal fraction on it. I googled what that was. I saw most ladies who were only 12-14 weeks with higher fetal fractions. My losses coupled with my health issues has me over analyzing everything it seems. [/quote]

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