Real Talk - Do GLP-1 Side Effects Ever Really Go Away?

[Anonymous]

Sounds awful

[Anonymous]

You need to change your injection location. And never take it on an empty stomach. Eat some protein first, then take your shot.

[Anonymous]

I had mild constipation the first few months. Other than that, I have had zero side effects. I am down 50 pounds after two years.

[Anonymous]

Anonymous wrote: OP, thanks for asking this question, I'm wondering it too. I am on week 6, almost 7, of Wegovy at a .25 dose, which is what I started at. I have not increased the dosage at all. Every week i have at least one day, if not more than 1, where I feel like I have a stomach bug. At the risk of TMI I have projectile liquids coming out from both ends. It feels totally unsustainable to have that as a side effect ongoing! I don't know if it's worth a conversation with my PCP about trying a different drug, or if this is just the physical cost of GLP-1s and most people live with it, but while I'm thrilled with the weightloss, I have little kids an fulltime job that cannot sustain these side effects!

Op I started on wegovy had sane issues stopped after four months

Now on zepbound same dosage as you and not sustainable in my opinion I’ve been on it a month it sucks. I told my doctor I would try another month but if it stays like this I’m not willing to term this bad and not function to lose weight

[Anonymous]

Been on Mounjaro (same as Zepbound) since September 2022 so over 3 years. No issues with side effects anymore.

I’m going great! Lost 70lbs and have maintained well. I changed my diet, workout regularly and feel great!

[Anonymous]

Yes, maintenance is very differently than weightloss. I had all kinds of temporal side effects and nothing in maintenance.

[Anonymous]

I have been on 15 weeks (Wegovy) with no side effects aside from constipation which is alleviated with coffee and regular fiber supplements. Down 30lbs with little change to my eating habits (eat what I want...just FAR less of it!)

[Anonymous]

Mine disappeared suddenly at 11 weeks in. I thought it was a fluke at first, but I am 18 weeks in now and they are still gone.

[Anonymous]

Yes. It took me 4-5 months and they went away. I’m now on a maintenance dose and zero side effects. I did have side effects on this dose when ramping up.