I ate more on zepbound and lost 20 lbs

Anonymous
You probably feel fuller and are eating less. I know I can feel like I stuffed myself when I only ate a normal portion, the same feeling as when I had seconds without Glp-1.
Anonymous
I doubt you are eating “way more.” The laws of physics still apply to you.
Anonymous
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:Same.

Weight watchers tracking so 19 points but essentially 1200 calories to maintain weight and being overweight by 15 lbs. looking at obese in a few more lbs.

I’ve lost 10lbs in 16 weeks eating about 1500-1800 calories.


I call BS that you are 1200 cal/ day EVERY DAY for 1-2 months and lost nothing. A. Most people can not stick to 1200 cal a day. They tend to do it for a few days, get ravenous then over eat and start again. B. They are not consistent- meaning they eat these calories 90-100% of the time for a solid month. c. Losing while eating 1500-1800 cal for someone who is overweigh/weights more than 150 lbs is right on track for what they need to be in a deficit and lose weight. The thing is we are told we need to eat 1200 cal to lose weight so assume more that that will not work. Sure you will lose faster with a larger deficit, but rarely do people actually stick to that large deficit long enough to lose.

I say this as someone who has been on a GLP1 and I lost weight because i was more able to stick to my calorie target because I wasn't hungry all the time. got full faster and was able to stop eating vs continuing to eat even when the food was tasty.


It was 1200 for a year and I lost 10 lbs the 1st 3 months. Then I was stuck. I never lost “fast”.

I tracked points but WW added calories to their app recently so I can look at my calories.

My nutritionist thought 1200 was too low but that’s how WW worked for me . I was 185 down to 175. I’m 5’8” But got stuck for 9 months.

Due to medical issues I was motivated but stuck. So I went on a GLP-1.


again I would bet that you were not really only eating 1200 calories or not really eating that consistently. If i were to lock you in a room with a controlled diet I would guarantee you would lose weight on 1200 calorie.

Now why is that? Eating 1200 calories for someone who weights 175+ lbs is incredibly difficult and nearly impossible without an appetite suppressant. So people don't CONSISTENTLY stick to it and losing weight is about consistency. If you are only 70% consistent it will feel really hard like you are doing "everything you can" but in reality it is not enough. To lose weight you need to be 85-100% consistent, that is hitting your calorie target at least 6 days a week.

now why do people lose weight while "eating more" when they go form "eating 1200 calories" to 1500-1600? Well the higher calories are still a deficit, but more realistic and manageable so they are more likely to actually meet that target with greater consistency. vs when eating 1200 calories where they eat that for a few days, overeat because they are starving, then getting back on the wagon and going through the starve- overeat cycle over and over again.
Anonymous
I am eating more and losing as well. Or rather, I’ve increased my BMR and can maintain at a higher calorie intake, and lose more easily when I cut calories.

People posting here have very very simplistic ideas of how metabolism and weight loss work. I believe you OP.
Anonymous
Thanks, OP here - I don’t really care if you all don’t believe me, as what does it matter, but it’s absolutely true. I used to have to skip a meal to avoid gaining even more weight. Studies have shown that some people are indeed able to eat more and lose on these meds. It will be interesting to find out why that is.
Anonymous
Anonymous wrote:I am eating more and losing as well. Or rather,
I’ve increased my BMR
and can maintain at a higher calorie intake, and lose more easily when I cut calories.

People posting here have very very simplistic ideas of how metabolism and weight loss work. I believe you OP.


so you're saying Zepbound changes metabolism for you and op?
Anonymous
Anonymous wrote:Thanks, OP here - I don’t really care if you all don’t believe me, as what does it matter, but it’s absolutely true. I used to have to skip a meal to avoid gaining even more weight. Studies have shown that some people are indeed able to eat more and lose on these meds. It will be interesting to find out why that is.


Can you post the studies?
Anonymous
Anonymous wrote:
Anonymous wrote:I am eating more and losing as well. Or rather,
I’ve increased my BMR
and can maintain at a higher calorie intake, and lose more easily when I cut calories.

People posting here have very very simplistic ideas of how metabolism and weight loss work. I believe you OP.


so you're saying Zepbound changes metabolism for you and op?


I’m saying it did. And yes, there are studies out there about this. It treats insulin resistance.
Anonymous
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:I am eating more and losing as well. Or rather,
I’ve increased my BMR
and can maintain at a higher calorie intake, and lose more easily when I cut calories.

People posting here have very very simplistic ideas of how metabolism and weight loss work. I believe you OP.


so you're saying Zepbound changes metabolism for you and op?


I’m saying it did. And yes, there are studies out there about this. It treats insulin resistance.


Google says...

Although basal metabolic rate (BMR) is involved in glucose homeostasis, existing evidence regarding its association with insulin resistance (IR) remains inconsistent across populations.
Jul 1, 2025

BMC Endocrine Disorders
https://bmcendocrdisord.biomedcentral.com › articles
Association of predicted basal metabolic rate and insulin ...https://bmcendocrdisord.biomedcentral.com/articles/10.1186/s12902-025-01976-3#:~:text=Although%20basal%20metabolic%20rate%20(BMR,IR)%20remains%20inconsistent%20across%20populations.
Anonymous
Anonymous wrote:Thanks, OP here - I don’t really care if you all don’t believe me, as what does it matter, but it’s absolutely true. I used to have to skip a meal to avoid gaining even more weight. Studies have shown that some people are indeed able to eat more and lose on these meds. It will be interesting to find out why that is.


Agreed. I don’t know why people get on here and spread doubt.
It’s true for me, too.
Anonymous
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:Same.

Weight watchers tracking so 19 points but essentially 1200 calories to maintain weight and being overweight by 15 lbs. looking at obese in a few more lbs.

I’ve lost 10lbs in 16 weeks eating about 1500-1800 calories.


I call BS that you are 1200 cal/ day EVERY DAY for 1-2 months and lost nothing. A. Most people can not stick to 1200 cal a day. They tend to do it for a few days, get ravenous then over eat and start again. B. They are not consistent- meaning they eat these calories 90-100% of the time for a solid month. c. Losing while eating 1500-1800 cal for someone who is overweigh/weights more than 150 lbs is right on track for what they need to be in a deficit and lose weight. The thing is we are told we need to eat 1200 cal to lose weight so assume more that that will not work. Sure you will lose faster with a larger deficit, but rarely do people actually stick to that large deficit long enough to lose.

I say this as someone who has been on a GLP1 and I lost weight because i was more able to stick to my calorie target because I wasn't hungry all the time. got full faster and was able to stop eating vs continuing to eat even when the food was tasty.


It was 1200 for a year and I lost 10 lbs the 1st 3 months. Then I was stuck. I never lost “fast”.

I tracked points but WW added calories to their app recently so I can look at my calories.

My nutritionist thought 1200 was too low but that’s how WW worked for me . I was 185 down to 175. I’m 5’8” But got stuck for 9 months.

Due to medical issues I was motivated but stuck. So I went on a GLP-1.


again I would bet that you were not really only eating 1200 calories or not really eating that consistently. If i were to lock you in a room with a controlled diet I would guarantee you would lose weight on 1200 calorie.

Now why is that? Eating 1200 calories for someone who weights 175+ lbs is incredibly difficult and nearly impossible without an appetite suppressant. So people don't CONSISTENTLY stick to it and losing weight is about consistency. If you are only 70% consistent it will feel really hard like you are doing "everything you can" but in reality it is not enough. To lose weight you need to be 85-100% consistent, that is hitting your calorie target at least 6 days a week.

now why do people lose weight while "eating more" when they go form "eating 1200 calories" to 1500-1600? Well the higher calories are still a deficit, but more realistic and manageable so they are more likely to actually meet that target with greater consistency. vs when eating 1200 calories where they eat that for a few days, overeat because they are starving, then getting back on the wagon and going through the starve- overeat cycle over and over again.


You’re so invested in your erroneous belief. Good luck with life. Your black and white thinking will not serve you well.
Anonymous
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:I am eating more and losing as well. Or rather,
I’ve increased my BMR
and can maintain at a higher calorie intake, and lose more easily when I cut calories.

People posting here have very very simplistic ideas of how metabolism and weight loss work. I believe you OP.


so you're saying Zepbound changes metabolism for you and op?


I’m saying it did. And yes, there are studies out there about this. It treats insulin resistance.


My SIL works with insulin resistant patience and she talks about this ozempic vs insulin .
Anonymous
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:I am eating more and losing as well. Or rather,
I’ve increased my BMR
and can maintain at a higher calorie intake, and lose more easily when I cut calories.

People posting here have very very simplistic ideas of how metabolism and weight loss work. I believe you OP.


so you're saying Zepbound changes metabolism for you and op?


I’m saying it did. And yes, there are studies out there about this. It treats insulin resistance.


Google says...

Although basal metabolic rate (BMR) is involved in glucose homeostasis, existing evidence regarding its association with insulin resistance (IR) remains inconsistent across populations.
Jul 1, 2025

BMC Endocrine Disorders
https://bmcendocrdisord.biomedcentral.com › articles
Association of predicted basal metabolic rate and insulin ...https://bmcendocrdisord.biomedcentral.com/articles/10.1186/s12902-025-01976-3#:~:text=Although%20basal%20metabolic%20rate%20(BMR,IR)%20remains%20inconsistent%20across%20populations.


It also says:

Zepbound (tirzepatide) increases insulin sensitivity by stimulating the pancreas to release more insulin in response to glucose and by improving how the body uses insulin. As a dual GLP-1/GIP receptor agonist, it mimics the actions of two natural hormones, which lowers blood sugar levels and improves how the body handles insulin.

Increased insulin sensitivity promotes weight loss because it allows the body to use glucose more effectively for energy instead of storing it as fat. With higher sensitivity, the body requires less insulin, which reduces the signals for fat storage and can lead to a decrease in overall body fat and weight. In contrast, insulin resistance encourages the body to store fat, making weight loss more difficult.


—why are you so pressed about this PP?
Anonymous
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:I am eating more and losing as well. Or rather,
I’ve increased my BMR
and can maintain at a higher calorie intake, and lose more easily when I cut calories.

People posting here have very very simplistic ideas of how metabolism and weight loss work. I believe you OP.


so you're saying Zepbound changes metabolism for you and op?


I’m saying it did. And yes, there are studies out there about this. It treats insulin resistance.


Google says...

Although basal metabolic rate (BMR) is involved in glucose homeostasis, existing evidence regarding its association with insulin resistance (IR) remains inconsistent across populations.
Jul 1, 2025

BMC Endocrine Disorders
https://bmcendocrdisord.biomedcentral.com › articles
Association of predicted basal metabolic rate and insulin ...https://bmcendocrdisord.biomedcentral.com/articles/10.1186/s12902-025-01976-3#:~:text=Although%20basal%20metabolic%20rate%20(BMR,IR)%20remains%20inconsistent%20across%20populations.


It also says:

Zepbound (tirzepatide) increases insulin sensitivity by stimulating the pancreas to release more insulin in response to glucose and by improving how the body uses insulin. As a dual GLP-1/GIP receptor agonist, it mimics the actions of two natural hormones, which lowers blood sugar levels and improves how the body handles insulin.

Increased insulin sensitivity promotes weight loss because it allows the body to use glucose more effectively for energy instead of storing it as fat. With higher sensitivity, the body requires less insulin, which reduces the signals for fat storage and can lead to a decrease in overall body fat and weight. In contrast, insulin resistance encourages the body to store fat, making weight loss more difficult.


—why are you so pressed about this PP?


Oh and here’s the study I was thinking about, if you’re still skeptical:

https://www.cell.com/cell-metabolism/abstract/S1550-4131(25)00114-7?rss=yes

The TLDR is that something about the GIP/GLP-1 combo helps people avoid adapting to lower calories and storing fat (I call it my Siberian hibernation mode… my Slavic ancestors probably benefitted from staying plump on very few calories). The medication keeps your internal fire going when you’re dieting, which is helpful for people who have a tendency to get fat on air.
Anonymous
I eat the exact same healthy diet. Only difference is that now I lose weight. V e r y slowly but losing.
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