| You probably feel fuller and are eating less. I know I can feel like I stuffed myself when I only ate a normal portion, the same feeling as when I had seconds without Glp-1. |
| I doubt you are eating “way more.” The laws of physics still apply to you. |
again I would bet that you were not really only eating 1200 calories or not really eating that consistently. If i were to lock you in a room with a controlled diet I would guarantee you would lose weight on 1200 calorie. Now why is that? Eating 1200 calories for someone who weights 175+ lbs is incredibly difficult and nearly impossible without an appetite suppressant. So people don't CONSISTENTLY stick to it and losing weight is about consistency. If you are only 70% consistent it will feel really hard like you are doing "everything you can" but in reality it is not enough. To lose weight you need to be 85-100% consistent, that is hitting your calorie target at least 6 days a week. now why do people lose weight while "eating more" when they go form "eating 1200 calories" to 1500-1600? Well the higher calories are still a deficit, but more realistic and manageable so they are more likely to actually meet that target with greater consistency. vs when eating 1200 calories where they eat that for a few days, overeat because they are starving, then getting back on the wagon and going through the starve- overeat cycle over and over again. |
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I am eating more and losing as well. Or rather, I’ve increased my BMR and can maintain at a higher calorie intake, and lose more easily when I cut calories.
People posting here have very very simplistic ideas of how metabolism and weight loss work. I believe you OP. |
| Thanks, OP here - I don’t really care if you all don’t believe me, as what does it matter, but it’s absolutely true. I used to have to skip a meal to avoid gaining even more weight. Studies have shown that some people are indeed able to eat more and lose on these meds. It will be interesting to find out why that is. |
so you're saying Zepbound changes metabolism for you and op? |
Can you post the studies? |
I’m saying it did. And yes, there are studies out there about this. It treats insulin resistance. |
Google says... Although basal metabolic rate (BMR) is involved in glucose homeostasis, existing evidence regarding its association with insulin resistance (IR) remains inconsistent across populations. Jul 1, 2025 BMC Endocrine Disorders https://bmcendocrdisord.biomedcentral.com › articles Association of predicted basal metabolic rate and insulin ...https://bmcendocrdisord.biomedcentral.com/articles/10.1186/s12902-025-01976-3#:~:text=Although%20basal%20metabolic%20rate%20(BMR,IR)%20remains%20inconsistent%20across%20populations. |
Agreed. I don’t know why people get on here and spread doubt. It’s true for me, too. |
You’re so invested in your erroneous belief. Good luck with life. Your black and white thinking will not serve you well. |
My SIL works with insulin resistant patience and she talks about this ozempic vs insulin . |
It also says: Zepbound (tirzepatide) increases insulin sensitivity by stimulating the pancreas to release more insulin in response to glucose and by improving how the body uses insulin. As a dual GLP-1/GIP receptor agonist, it mimics the actions of two natural hormones, which lowers blood sugar levels and improves how the body handles insulin. Increased insulin sensitivity promotes weight loss because it allows the body to use glucose more effectively for energy instead of storing it as fat. With higher sensitivity, the body requires less insulin, which reduces the signals for fat storage and can lead to a decrease in overall body fat and weight. In contrast, insulin resistance encourages the body to store fat, making weight loss more difficult. —why are you so pressed about this PP? |
Oh and here’s the study I was thinking about, if you’re still skeptical: https://www.cell.com/cell-metabolism/abstract/S1550-4131(25)00114-7?rss=yes The TLDR is that something about the GIP/GLP-1 combo helps people avoid adapting to lower calories and storing fat (I call it my Siberian hibernation mode… my Slavic ancestors probably benefitted from staying plump on very few calories). The medication keeps your internal fire going when you’re dieting, which is helpful for people who have a tendency to get fat on air. |
| I eat the exact same healthy diet. Only difference is that now I lose weight. V e r y slowly but losing. |